J GENE MED
ISSN：1099-498X E-ISSN：1521-2254 出版商：Wiley 国家：ENGLAND 周期：Monthly
| 收录情况 | h-index：87 CiteScore：4.00 |
The aims and scope of The Journal of Gene Medicine include cutting-edge science of gene transfer and its applications in gene and cell therapy| genome editing with precision nucleases| epigenetic modifications of host genome by small molecules| siRNA| microRNA and other noncoding RNAs as therapeutic gene-modulating agents or targets| biomarkers for precision medicine| and gene-based prognostic/diagnostic studies. Key areas of interest are the design of novel synthetic and viral vectors| novel therapeutic nucleic acids such as mRNA| modified microRNAs and siRNAs| antagomirs| aptamers| antisense and exon-skipping agents| refined genome editing tools using nucleic acid /protein combinations| physically or biologically targeted delivery and gene modulation| ex vivo or in vivo pharmacological studies including animal models| and human clinical trials. Papers presenting research into the mechanisms underlying transfer and action of gene medicines| the application of the new technologies for stem cell modification or nucleic acid based vaccines| the identification of new genetic or epigenetic variations as biomarkers to direct precision medicine| and the preclinical/clinical development of gene/expression signatures indicative of diagnosis or predictive of prognosis are also encouraged.
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